শুক্রবার, ৩০ নভেম্বর, ২০১২

Stock Downgrades: Taser Suffers Stunning Setback | Stocks ...

MINYANVILLE ORIGINAL Fiscal cliff, meet Jimmy Cliff. Shares jumped after Washington belatedly awoke to the wisdom of the jaunty Jamaican, who?long ago concluded?that ?You can get it if you really want. But you must try, try and try. Try and try.? Renewed efforts in our nation?s capital to solve the coming calamity of tax hikes and spending cuts encouraged investors, with markets ending at session highs after President Obama said he?hoped to conclude a deal by Christmas.
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And in the spirit of the season ? yes, Virginia, there is indeed a Santa Claus, at least if you?re a tobacco company. Witness Richmond cigarette stock?Altria?(MO) advancing 0.78% even as the?industry was confronted with yet another can of worms. From high tar to?tar heels,?BP Plc?(BP) was another name to shrug off?negative news, edging up 0.31% despite ongoing fallout from its 2010 oil spill in the Gulf of Mexico.
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Today in economics, analysts expect October pending home sales to tick up at 10:00 a.m. Eastern. In earnings action,?Barnes & Noble (BKS), Cracker Barrel Old Country Store (CBRL), Kroger (KR), Pacific Sunwear of California (PSUN), Splunk (SPLK), Tiffany (TIF), Ulta Salon (ULTA), and Zumiez?(ZUMZ) are all due to reveal results.
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Activision Blizzard?(ATVI): Shares are now Neutral from Buy at Sterne Agee, whose concerns include risks related to console transition.
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British Sky Broadcasting?(BSYBY): The media giant gets moved to Underperform from Perform at Jefferies.
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Cree Inc.?(CREE): CREE is cut to Hold from Buy at Deutsche Bank.
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EZchip?(EZCH): Chardan Capital slashes the stock to Sell from Hold due to a lack of capital expenditure by service providers on wireline projects.
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Taser International?(NASDAQ:TASR) The electroshock stun gun maker, up 54.72% over the past 12 months, is tumbling 2.88% before today?s opening bell after getting taken to Neutral from Overweight at JPMorgan.

(See also: New Stock Coverage: Messing With Texas Instruments and Stock Upgrades: Bulls Run on Nike.)

No positions in stocks mentioned.

The information on this website solely reflects the analysis of or opinion about the performance of securities and financial markets by the writers whose articles appear on the site. The views expressed by the writers are not necessarily the views of Minyanville Media, Inc. or members of its management. Nothing contained on the website is intended to constitute a recommendation or advice addressed to an individual investor or category of investors to purchase, sell or hold any security, or to take any action with respect to the prospective movement of the securities markets or to solicit the purchase or sale of any security. Any investment decisions must be made by the reader either individually or in consultation with his or her investment professional. Minyanville writers and staff may trade or hold positions in securities that are discussed in articles appearing on the website. Writers of articles are required to disclose whether they have a position in any stock or fund discussed in an article, but are not permitted to disclose the size or direction of the position. Nothing on this website is intended to solicit business of any kind for a writer's business or fund. Minyanville management and staff as well as contributing writers will not respond to emails or other communications requesting investment advice.

Copyright 2011 Minyanville Media, Inc. All Rights Reserved.

Source: http://www.minyanville.com/trading-and-investing/stocks/articles/Stock-Downgrades253A-Taser-Suffers-Stunning-Setback/11/29/2012/id/46201

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US birth rates hit record lows; immigrants' plunge

American women had far fewer babies after the onset of the Great Recession, which made 2011 the year with the nation?s lowest recorded birth rate. But it is immigrant women, specifically Mexican immigrant women, who had the steepest drop in births, a 23 percent lower birth rate between 2007 and 2010. ?By comparison, the drop during those years for U.S.-born women was 6 percent, ?and among all foreign-born women it was 14 percent.

According to the new Pew Research Center report released today, it was not just foreign-born Latinas who had fewer children. ?The authors,?demographers D?Vera Cohn and Gretchen Livingston, report that ?U.S.-born Hispanic women also had larger birth rate declines in the years between 2007 and 2010 than women of other ethnic or racial groups.

The numbers tell the picture quite clearly. Between 1990 and 2010, for example, the birth rate among U.S.-born Hispanic women dropped from 82.4 percent to 65.4 percent, a 21-point decline. ?Among foreign-born Latinas, there was a 30 percent drop from 1990 to 2010. ? And during the Great Recession years, between 2007 and 2010, births to Mexican women went down from 455,000 births in 2007 to 346,000 ? a 24 percent drop.

While the authors say the report does not address the reasons for the birth declines after 2007, they point out previous Pew Research analysis which finds ?that the recent fertility decline is closely linked to economic distress.? ?The report notes that states with the largest economic declines from 2007 to 2008 were most likely to see fertility declines from 2008 to 2009. ?Hispanics had the largest decline in household wealth ? 66 percent ? during the Great Recession, as well as higher unemployment and poverty rates.

The report?s findings do not surprise Leticia Mederos, vice president of the National Partnership for Women and Families. ?The size of a family is clearly an issue of economic security to so many Latino families, and very connected to pocketbook issues,? she notes.

It is important to note, however, that immigrants and their families are projected to account for 82 percent of the U.S. population by 2050. ?In fact, the 23 percent share of all 2010 births to foreign-born mothers was higher than the 17 percent share of women immigrants ages 15 to 44. ?And of all Hispanic births in 2010, 56 percent were to immigrant mothers.

One interesting finding is the age at which immigrant women have children. More immigrant women over the age of 35 give birth than do U.S.- born women. ?In 2010, 33 percent of births to women aged 35 or older were among immigrant women.? Conversely, very few foreign-born women are teen moms (5 percent) in part because of the age profile of immigration.

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Source: http://nbclatino.com/2012/11/29/report-u-s-birth-rates-hit-record-lows-largest-drop-among-immigrant-latinas/

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Is Cheap Hosting A Reliable Web Hosting Company Find Out The ...

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বৃহস্পতিবার, ২৯ নভেম্বর, ২০১২

Colombia, FARC wrap up first round of peace talks

HAVANA (Reuters) - Colombia's lead negotiator gave a muted assessment on Thursday of progress in talks aimed at ending a five-decade-long war with Marxist-led rebels, as negotiators wrapped up their initial round of meetings in the Cuban capital.

Former Colombian Vice President Humberto de la Calle's words contrasted with earlier, more exuberant rebel pronouncements that things were going well in a possible indication that nothing major has been agreed upon in the still-fledgling talks.

"We have finished the first round of direct conversations. I can say ? we have advanced as expected," de la Calle, wearing a black suit and white shirt, but no tie, told reporters at the Havana convention center where talks began on November 19 and will resume December 5.

"We will not move conversations at the table to the microphones. More than speeches, we want concrete results," he said. "When there is relevant information, we will make it public in an opportune manner."

The bloody conflict at issue, in which tens of thousands of people have died, dates back to 1964 when the FARC, or Revolutionary Armed Forces of Colombia, formed as a communist agrarian movement that later turned to the illicit drug trade, kidnappings and extortion to sustain itself. Millions of people have been displaced by the war.

FARC representatives have spoken daily going into the talks, but so far have held to an agreement not to discuss what is being said at the negotiating table.

On Thursday, Dutch rebel Tanja Nijmeijer read a statement expressing solidarity with the Palestinian cause in the Middle East. She wore all black clothes, with a checked Palestinian scarf around her neck.

The rebels had scheduled a press conference for later on Thursday.

Previous attempts at peace ended in shambles, but a 10-year-long, U.S.-backed military offensive has weakened the FARC to the point that the government believes it may be ready for a negotiated end to the war.

The talks have begun with the complicated issue of rural development, with four equally difficult topics - ending the war, the political and legal future of the rebels, the drug trade and compensation for war victims - to follow.

President Juan Manuel Santos has said he wants an agreement within nine months, but the rebels say the process could take much longer.

(Writing by Jeff Franks; Editing by Tom Brown and Cynthia Osterman)

Source: http://news.yahoo.com/colombia-farc-wrap-first-round-peace-talks-210051501.html

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Commercial Mortgage For Retail | Commercial Mortgages ...

commercial mortgage for shops Whether a sole trade, considering the move into the retail sector, an existing business owner seeking to expand a portfolio or an entrepreneur struggling to maintain the repayments on a current finance agreement; the first three quarters of 2012 have made for anything but the ideal commercial environment.

With continued talk of a struggling economy, banking lending at a low and consumer activity stagnate at best; the retail business owner is in dire need of vital commercial finance but where does the right solution lie?

As lending to small and medium businesses? struggles to improve; the commercial mortgage broker is now, actively available to provide the finance required for start-ups and existing businesses. Considered the seamless, stable and securest form of finance; the commercial mortgage is considered the ideal lending for all retail businesses.

Why A Commercial Mortgage?

In the face of the struggling economy, property rental may seem like the immediate ?must have? solution however, with instability continuing to cloud the economy, rising rent rates, inflation changes and so forth; stability will lie only with a solid and secure financial agreement.

A commercial mortgage, dependent upon the terms agreed between the lender and borrower, can provide security for the duration of the?borrowing?period and in the hands of the right financial specialist; clients will be strictly matched only to the appropriate lender.

The benefits of a commercial retail mortgage include:

  • Vital funds for business expansion
  • Cash injection
  • Fixed Monthly Payment (Ideal for cash flow management)
  • Comfortable business growth
  • Increased profitability
  • Property ownership

Retail Financing

Almost all commercial property can be considered suitable for retail financing however, the common retail businesses that possess the potential to achieve a mortgage include:

  • Food Markets
  • Full Serviced Restaurants
  • Hairdressers
  • Bookies
  • Newsagent
  • Grocery Store
  • Furniture Stores
  • Clothing Stores
  • Toy Stores
  • Electronics

Although banks are continuing to withhold commercial finance; the alternative lender is able to assist with whatever the financial requirements will be. Whether you have spent months facing rejection from the high street lender or have only just been faced with the need for commercial finance; the alternative lender is a proven route of success in business finance:

  • A potential 100% of the sum required for a new property purchase (dependent on LTV and additional security)
  • Re-Mortgaging for those struggling with a current deal or perhaps even looking to capitalise on the low interest rates.
  • Additional lending to cover any other financial needs (store changes, new stock purchasing, business rates)

With access to a growing portfolio of lenders, the scope for business lending is far greater with a specialist commercial broker.

bank of england lending statistics

The Decline in Lending to the Small Business

Official Statistics courtesy of the Bank of England

What Do I Need To Do?

In order to begin a successful application process for a retail mortgage, your business will need to provide a wealth of information and documentation that will play a part in determining your credibility, and viability for a loan:

  • Account records for the previous three years
  • Profit and loss predictions
  • Previous bank statements (amount will be dependent upon the lender)
  • Evidence of successful trading and cash flow figures
  • Proof of experience.
  • Business proposal if necessary

The amount of information and documentation required will be dependent upon the lender you choose to deal with however; such figures are considered vital in the application process. By analysing as much statistical information as possible, using the LTV or DSCR ratios; the viability and risk level of lending to your business will be easily determined.

Rest assured that, in the event that a commercial mortgage is not deemed suitable for your business; the right broker company will, if applicable, offer alternative financial solutions.

Where Do I Find The Right Commercial Mortgage Broker?

Finding the right lender can be a daunting factor; after-all with trusts in banking at an all-time low; how can you be sure which lender is the most trusted?

When in need of a commercial mortgage, what you must initially consider is the level of experience the lender in question is in possession off; is the company strictly a commercial broker? If so, just what forms of lending do they offer? What experience do they have? Can they provide proven evidence of results?

For many, it may seem viable to consider working with a broker service specialising in all types of mortgages, including residential as that can only mean the experience of the specialists is advanced can it not? Unfortunately, the broader the offering, the less specialised the portfolio and opportunity for lending.

Financial experts argue that, when seeking commercial lending a specialist commercial mortgage broker is ideal. As a company; the level of expertise will be highly specialised and the source of lenders will be refined; providing a far better scope for your retail business to achieve the ideal financial solution.

Taking the Step

The purchase and retainment of a business premises is the logical step for retail success which is why a commercial mortgage is considered the most suitable form of finance. Often running between fifteen and twenty years, your business will have the security of a suitable fixed payment and the end goal of a property purchase; plus points never possible with property rental.

If you are considering taking the step into the retail market, wish to expand your current venture or secure your success during a time of struggle than a commercial mortgage can be the ideal solution for your business.

Why not contact a mortgage broker today and give your retail venture a vital boost?

Source: http://www.charlestonfinancial.co.uk/commercial-mortgage-for-retail/

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Equipment finance in Brisbane | Car Finance, Loans & Leasing Blog ...

Roche Finance offers a range of innovative car finance, novated lease and equipment finance products to individuals and businesses in Brisbane, Gold Coast, Townsville, Cairns, Toowoomba, Rockhampton and throughout Queensland (Qld).

Whether you are purchasing from a car dealer, car auction, private sale or you want to re-finance your existing car loan, we can tailor a finance solution to meet your individual needs.

Source: http://h3sean.typepad.com/blog/2012/11/equipment-finance-in-brisbane-car-finance-loans-leasing-blog-roche-finance.html

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PFT: Harbaugh nearly faced mutiny in October

John HarbaughAP

The Ravens are 9-2, but it hasn?t been an easy season.? Apart from key injuries and periodic ineffectiveness and a defense that ain?t what it used to be, coach John Harbaugh had to deal with an unexpected uprising last month.

The moment came, according to Mike Silver of Yahoo! Sports, on Halloween morning.? Back from a bye-week break after a backbreaking loss to the Texans, Harbaugh told the team that they?d be practicing in full pads.? Several veteran players openly challenged their head coach.

?It was practically a mutiny,? a Ravens player told Silver.? ?It came very close to getting out of control. But the way Coach Harbaugh handled it was amazing.? He let people have their say, and he listened, and he explained himself, and pretty soon it was like a big group-therapy session.? In the end, a lot of positive things were said.? We didn?t practice in pads, but we came out of there stronger as a group.?

Coincidentally (or not), the Ravens haven?t lost since then.

?I?ve never seen a head coach handle anything like that as well as he did,? a Ravens assistant who attended the meeting told Silver.? ?There were some things said where we were like, Damn.

?A lot of coaches would have acted like dictators and been very sensitive about the way their authority was being questioned.? John said, ?Hey, let?s talk about this.?? He showed great leadership.? Instead of worrying that it would make him seem weak, he turned it into a strength.?

Harbaugh realizes the value of encouraging players to speak their mind.

?I wasn?t threatened by it,? Harbaugh said.? ?That?s the main thing.? And, you know, they had some good points, and I had some good points.? Other guys stood up and said some great things.? To me, it embodied everything that you should have on a team.

?The point was that, we have what I call ?Open Mic,? and we can all say anything that we need to say and have to say. You know then that you?re responsible ? when you say it, everybody?s gonna hear it, so you?d better make it your best stuff.

?That brings out the best.? Otherwise, it?s ?Why are they sneaking around talking behind corners??? You know what I mean?? If you?ve got something, you put it right out here in front of me.? I?m man enough to handle it.? If you?re right, then you?re right!? It?s OK to be right.? But more important it?s OK to be wrong.? And it?s OK for me to be wrong, too.?

By being willing to admit that he?s wrong and make changes, Harbaugh could be poised to take his team right to the Super Bowl.

In fact, the only thing Harbaugh may have done wrong in this episode is to let it be known what happened.? Now, other coaches facing similar challenges may opt not to be hardheaded, which could help their own teams play better, possibly when playing the Ravens.

Source: http://profootballtalk.nbcsports.com/2012/11/28/john-harbaugh-nearly-faced-a-mutiny-n-october/related

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বুধবার, ২৮ নভেম্বর, ২০১২

Americans in Israel sue State Department for Providing aid to Palestinian terrorists illegally

Obama?s White House and State Department providing aid to Gaza in violation of guidelines passed by law? You don?t say.

State Department, White House ignored transparency requirements in delivering Palestinian aid, allowing some of the money to flow to the likes of Hamas, plaintiffs claim.

A group of 24 Americans living in Israel, some of them victims of terror, on Tuesday filed a?civil action lawsuit against the United States government?over what they claim is its funding of Palestinian terrorism in the West Bank and the Gaza Strip.?The plaintiffs were being represented by?the Tel Aviv-based Shurat HaDin ? Israel Law Center, a legal advocacy group that combats terror organizations.

The lawsuit, which was filed in Washington, DC, contends that the State Department and Secretary of State Hillary Clinton ignored Congressional safeguards and transparency?requirements attached to US aid to the Palestinian Authority, thus allowing for the funneling of funds to Hamas, the Popular Front for the Liberation of Palestine?(PFLP), and the Palestine Liberation Front.?It also accuses the White House of not complying with the regulations and reporting obligations governing?presidential waivers which facilitate emergency funding to the?Palestinians.

?I just want justice,? said Stuart Hersh, one of the plaintiffs, an elderly Jerusalem resident and victim of a terror attack on Ben Yehuda Street in the same city in 1997, which caused him brain damage and left him partially disabled. ?I am against the American government indirectly financing Hamas ? the very people who try to kill me,? Hersh said by telephone, adding that he differentiates between ?humanitarian aid for the Palestinian people and supporting political agendas.?

Nitsana Darshan-Leitner, the Tel Aviv-based director of?Shurat HaDin told The Times of Israel that the State Department and USAID were particularly ?lax? in requiring?the Palestinians to ?utilize bank accounts and other transfer methods?that ensure transparency.??US funds have been?flowing to the terror groups as a?result of this noncompliance, Darshan-Leitner added.

?USAID?s funding of the PA, for example, is partially distributed to Gaza, where Hamas employees are paid, or Fatah, which still has anti-Israel elements in its charter,? Darshan-Leitner said.??The American people are opposed to terror and do not?want to fund it via their taxes.?

Karen Bell Eisenberg, an American-Israeli who lives outside Bethlehem in the West Bank, put it this way: ?I don?t begrudge Palestinian aid money. But I?m tired of my tax money [she works for an American company and pays taxes in the US] being used to fund the very people who are trying to kill me.?

The State Department, under the Palestinian?Anti-Terrorism Act, is prohibited from providing ?material support? to?banned terrorist groups.?Under that law, the State Department is required to?certify that the Palestinian government is committed to peace and?coexistence with Israel before distributing funds.

According to the advocacy group?s estimates, since the signing of?the Oslo Accords in 1993, the State Department, via?USAID, has given over $4 billion to Palestinians, with portions of that?funding illegally falling into the hands of terrorists. Over the last?four fiscal years, the average aid package has been roughly $600 million per year, compounded by the $200 million or so given annually to the United Nations Refugee Worker?s?Administration (UNRWA).

The suit asks the federal court to review the conduct of the State?Department and the safeguards on funds being distributed by USAID, and seeks to suspend future American aid to the?PA and UNRWA until all the Congressional regulations and?reporting requirements are fully complied with.

About Chuck Norton

Political issue strategist and communications professional. I write about politics, education, economics, morality and philosophy.

Source: http://politicalarena.org/2012/11/27/americans-in-israel-sue-state-department-for-providing-aid-to-palestinian-terrorists-illegally/

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Conservation Officer Report: Hunter Harassment | Sports ...

The Minnesota DNR provided the following summaries of last week's activities by Conservation Officers:

CO Mary Manning (Hovland) wrapped up deer hunting complaints and took information for use next deer season. A case of hunter harassment was investigated where other hunters sabotaged a stand so that it would collapse when used. Another incident was investigated where a hunter shot the top off a small pine tree less than 100 feet from a family?s home; the shot lined up with the house and a picnic table in the yard. Manning also handled equipment issues and answered questions about wolf hunting and trapping.

CO Darin Fagerman (Grand Marais) checked small game hunters and trapping activity during the week. He also worked on investigations of wild land arson fires and a bear guiding case. Trappers are reminded to check their trap tags to make sure they are legible.

CO Thomas Wahlstrom (Tofte) checked traps during the opening weekend of the fisher and pine marten season. Muzzleloader hunters were also checked. The officer appeared in court for a trial and followed up on past investigations. Enforcement action was taken for DAR, trapping and ATV violations.

CO John Velsvaag (Ely) checked up on several deer baiting complaints this past week. CO Velsvaag took several calls on the upcoming second wolf season. He also followed up on complaints of early pine marten trapping.

CO Marty Stage (Ely) worked on cases that were left over from the deer season. Time was spent putting away boats since the lakes are frozen up now. The second wave of hunters has shown up for wolf, muzzleloader, and marten and fisher trapping. Trappers are reminded that if they don?t want the conservation officer to alter their sets any more than is absolutely necessary, they should not roll their ID tags into a little ball. Doing this makes the tag difficult to read.

CO Anthony Bermel (Babbitt / Ely) reports the first snowstorm of the year and ice forming on the lakes, bringing winter sports here soon. An investigation from deer season was completed with enforcement action taken for hunting deer without a license and a rifle was seized. Whitefish netting was monitored. A busy wolf, muzzleloader deer, and fisher/marten opener was worked. Other enforcement action for the week included over limit of crappies, unregistered ATV, trespass, commercial records violation, fail to register deer, transport loaded gun in motor vehicle, no blaze orange while trapping, fail to validate marten site coupon, set trap on pole with illegal diameter, and no trapping license in possession.

Sgt. Keith Olson (Lake Superior Marine Unit) reports with the recent snowfall and more winter like temps the muzzleloader hunters enjoyed plenty of tracking snow. Several hunters checked over the weekend reported a slow start to the season. Snowmobile activity has started with the new snow. Calls and questions wrapped up from the firearms deer season. He assisted with cars in the ditch due to the slippery road conditions.

CO Matt Miller (Lake Superior Marine Unit) spent time wrapping up cases from deer season. A grant application was completed. Commercial and charter fishing violations were handled, and the season wrapped up for those operators as well. An early snowfall greeted marten/fisher trappers and muzzleloader hunters with some fresh tracking snow. Enforcement action was taken for ATV and commercial violations.

CO Troy Ter Meer (Lake Superior Marine Unit) spent the week checking commercial fishermen, checked some shore fishermen on Lake Superior, and worked on paperwork from the deer season. Enforcement action was taken for angling without a license.

Source: http://northshore.wdio.com/news/sports-recreation/52601-conservation-officer-report-hunter-harassment

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Shrubs lend insight into a glacier's past

ScienceDaily (Nov. 26, 2012) ? The stems of shrubs have given researchers a window into a glacier's past, potentially allowing them to more accurately assess how they're set to change in the future.

Their findings have been published 27 November in IOP Publishing's journal Environmental Research Letters, and show how a glacier's history of melting can be extended way past the instrumental record.

Much like the rings on a tree stump indicate how old it is, measuring the width of rings on the stem of a shrub can give a good indication of how well it has grown year on year. Under extreme environmental conditions, such as those close to a glacier, a shrub's growth relies heavily on summer temperatures, meaning the ring-width of a shrub can be used a proxy for glacial melting, which also relies heavily on summer temperatures.

Lead author of the study, Allan Buras, said: "In warm summers, shrubs grow more compared to cold summers. In contrast, a glacier's summer mass balance is more negative in warm summers, meaning there is more melting compared to cold summers.

"Big rings in shrubs therefore indicate comparably warm summers, and thus a strongly negative summer mass balance -- in other words, more melting."

The researchers, from the University of Greifswald, tested this theory on a local icecap in the Scandic Mountains of southern Norway. They took 24 samples of shrubs from a site close to the glacier and analysed their ring-widths.

Monthly precipitation and temperature data from a local climate station were retrieved from the Norwegian Meteorological Office, and the summer mass balance of the glacier, from 1963 to 2010, was retrieved from the existing literature.

Each of these data sets was then statistically tested to see if there was a correlation between them. The results showed a robust and reliable correlation between the ring-width of shrubs and the summer melting of the glacier.

"Our results show that it is possible to reconstruct glacier summer mass balance with shrub ring-width series and it is therefore theoretically possible to extent records of summer mass balance into the past," Buras continued.

The shrubs that were collected in the study were relatively young, only allowing for reliable reconstructions over the past 36 years, meaning they could not be used to extend the record of the glacier; however, the researchers are confident that this could have been achieved if longer-lived shrubs were selected.

Most of the available data on the mass balance of glaciers only spans several decades and there is some data missing, mainly because most glaciers are situated in hard-to-reach arctic and alpine areas.

With the possibility to extend the instrumental records of summer mass balance, researchers may gain a better understanding of how glaciers behave in the summer, which they can use to calibrate and verify their existing models.

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The above story is reprinted from materials provided by Institute of Physics.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Allan Buras, Martin Hallinger, Martin Wilmking. Can shrubs help to reconstruct historical glacier retreats? Environmental Research Letters, 2012; 7 (4): 044031 DOI: 10.1088/1748-9326/7/4/044031

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/strange_science/~3/OBMn89C92Ik/121126192759.htm

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Dr. Joseph Murray dies at 93; Nobel winner performed first kidney transplant

Since ancient times, surgeons have dreamed of transplanting healthy organs into patients disabled by disease and injury, but the human body's powerful immune system stymied all such attempts, leading many observers to conclude that the procedure was impossible.

But on Dec. 23, 1954, Dr. Joseph E. Murray of Peter Bent Brigham Hospital in Boston removed a healthy kidney from 23-year-old Ronald Herrick and implanted it in his identical twin, Richard, who was dying of severe kidney disease. The successful procedure proved that organ transplants were possible and opened an era in which organ transplants are now routinely performed on tens of thousands of patients each year.

Murray was later the first to transplant kidneys between non-identical siblings and to use organs from cadavers. His feats won him the 1990 Nobel Prize in Physiology or Medicine, an award he shared with Dr. E. Donnall Thomas, who performed the first bone-marrow transplant.

Murray died Monday at the hospital ? now known as Brigham and Women's Hospital ? where he performed his first transplant, after suffering a hemorrhagic stroke at his home on Thanksgiving Day. He was 93.

Murray received his first exposure to transplants during World War II while treating wounded soldiers at Valley Forge General Hospital in Pennsylvania. When patients did not have enough of their own skin for a graft, surgeons would transplant skin from other patients over the wounds. While these grafts would not survive for more than a few days, they would protect the wounds while they healed.

While preparing for surgeries with Col. James Barrett Brown, the chief of plastic surgery, Murray would often discuss the reasons for rejection. Brown thought that a close genetic relationship between the donor and the recipient would slow the rejection and he had, in fact, successfully grafted skin between identical twins in 1937. It was not until the 1950s and 1960s that biologists finally recognized that markers on the surface of cells called human leukocyte antigens, or HLAs, controlled the rejection process.

After the war, Murray began working with dogs in an attempt to perfect transplant techniques ? despite the scoffing of colleagues and a mentor's recommendation that he abandon the practice as a dead end. His research was considered "a fringe project," he wrote in his 2001 biography, "Surgery of the Soul."

In October 1954, the dying Herrick was referred to him for potential surgery. After much soul-searching and consultation with ethicists and religious leaders, Murray agreed. Although the hospital planned to keep the operation secret initially, news broke after Murray asked local police to check the fingerprints of the two brothers to ensure that they were twins.

Richard, who married one of his nurses at Brigham and had two children, fell victim to a recurrence of his kidney disease eight years later. Ronald survived until age 79.

The surgeon performed several more operations on identical twins, but recognized that this was a limited pool of recipients. His studies with dogs, however, showed that suppressing the patient's immune system with whole-body radiation could prolong survival, and in 1959 he began transplanting organs between fraternal twins. Success improved further when he added bone-marrow transplantation which, in effect, gave the recipient a new immune system compatible with the new organ.

One such patient lived for 29 more years.

These were drastic solutions, however, and would not work well for unrelated donors. The key to making transplants more accessible was the development of drugs that would suppress the immune system less drastically ? first azathioprine, then later cyclosporine and other drugs. In 1962, Murray and his team used such drugs to successfully implant a cadaver kidney from an unrelated donor into 23-year-old Mel Doucette.

In 1971, Murray retired as head of transplant surgery at Brigham and returned to his first love, plastic surgery. "At heart, I'm a reconstructive surgeon," he said at the time. His friend and colleague, the late Dr. Francis Moore, once noted that "Joe's the only guy who ever won a Nobel Prize for pursuing a hobby."

Murray used techniques originally developed by Dr. Paul Tessier of France to correct facial deformities by repositioning and moving forward the bones of the head and face. He traveled around the world to treat adults and children with severe facial deformities resulting from accidents, congenital conditions, cancer surgeries and other problems.

One of his best-known patients was Raymond Francis MacMillan, who suffered from Moebius syndrome ? a congenital condition involving severe heart and facial deformities. As a child, MacMillan was delivered to a mental institution because his parents could not deal with the condition.

When MacMillan was released at age 21, he was referred to Murray, who performed a series of surgeries that, among other things, repositioned the jaw so he could swallow normally, control saliva and smile. His appearance could not be made totally normal, but the surgery allowed him to function in the world and, Murray wrote, allowed "his inner self to grow and glow."

Joseph Edward Murray was born April 1, 1919, in Milford, Mass., about 30 miles southwest of Boston. From his earliest memory, he wrote in his Nobel biography, "I wanted to be a surgeon, possibly influenced by the qualities of our family doctor who cared for our childhood ailments."

He enrolled at the College of the Holy Cross, concentrating on Latin, Greek, English and philosophy, "assuming I'd receive ample science in medical school." He graduated from Harvard Medical School in 1943 and served in the Army until 1947. He spent his entire career at Brigham.

In 1986, Murray suffered a stroke. Although he recovered quickly and was cleared to return to the operating room, he decided to retire and "just enjoy the other aspects of my life," he said at the time.

Murray is survived by his wife of 67 years, the former Virginia "Bobby" Link; three sons, three daughters and 18 grandchildren.

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Source: http://feeds.latimes.com/~r/latimes/news/science/~3/pgvvFZR-7Jk/la-me-joseph-murray-20121128,0,3405643.story

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Rolling Stones storm London; New York next

CORRECTS REFERENCE TO NUMBER OF SHOWS - Mick Jagger, front centre, Ronnie Wood, left, with Keith Richards and Charlie Watts, right, of The Rolling Stones perform at the O2 arena in east London, Sunday, Nov. 25, 2012. The band are playing five gigs to celebrate their 50th anniversary, including two shows at London?s O2 and three more in New York. (Photo by Joel Ryan/Invision/AP)

CORRECTS REFERENCE TO NUMBER OF SHOWS - Mick Jagger, front centre, Ronnie Wood, left, with Keith Richards and Charlie Watts, right, of The Rolling Stones perform at the O2 arena in east London, Sunday, Nov. 25, 2012. The band are playing five gigs to celebrate their 50th anniversary, including two shows at London?s O2 and three more in New York. (Photo by Joel Ryan/Invision/AP)

CORRECTS REFERENCE TO NUMBER OF SHOWS - Mick Jagger, left and Keith Richards, of The Rolling Stones perform at the O2 arena in east London, Sunday, Nov. 25, 2012. The band are playing five gigs to celebrate their 50th anniversary, including two shows at London?s O2 and three more in New York. (Photo by Joel Ryan/Invision/AP)

CORRECTS REFERENCE TO NUMBER OF SHOWS - Mick Jagger, center, Keith Richards, Ronnie Wood, left, and Charlie Watts, right, of The Rolling Stones perform at the O2 arena in east London, Sunday, Nov. 25, 2012. The band are playing five shows to celebrate their 50th anniversary, including two shows at London?s O2 and three more in New York. (Photo by Joel Ryan/Invision/AP)

CORRECTS REFERENCE TO NUMBER OF SHOWS - Mick Jagger, center, Keith Richards, Ronnie Wood, left, and Charlie Watts, right, of The Rolling Stones perform at the O2 arena in east London, Sunday, Nov. 25, 2012. The band are playing four shows to celebrate their 50th anniversary, including two shows at London?s O2 and two more in New York. (Photo by Joel Ryan/Invision/AP)

(AP) ? The verdict is in: The Rolling Stones are back. They may look old, but they still sound young.

That was the consensus Monday as Britain's rock critics responded to the Stones 50th anniversary bash Sunday night, the first of five shows to commemorate their half century of rhythm and blues-tinged rock. It was the band's first London performance in five years, and their own advancing years had led some to be skeptical that they could still perform at the highest level.

They were led by the seemingly ageless Mick Jagger, whose strutting style has not been dimmed, and backed by brilliant guitarists Keith Richards and Ronnie Wood and the energetic drumming of Charlie Watts, who is now past 70 but shows no sign of slowing down. There was a stunning guest appearance by former Stone Mick Taylor, who stole the show during a searing performance of "Midnight Rambler" and a brief visit from former bassist Bill Wyman.

The Daily Mail's Jan Moir said the Stones had somehow beaten the aging process: "You might imagine that they had been worn down by life, by wives, by arthritis, by scandals old and new, by drugs, but no ? they seemed indestructible." She said their swampy, gritty sound remains unique after half a century.

Daily Telegraph reviewer Neil McCormick said the band exceeded all expectations. He described the weaving of the guitarists,?mixed with Jagger's blues harmonica, as a wonder.

"When looking for the secret of the Stones, it is perhaps that they actually listen to each other while they play, and almost lose themselves in it, while their brilliant frontman keeps it all together," he wrote.

Ebullient fans agreed with this assessment, as did the Guardian newspaper, which gave the performance four out of five stars.

Jagger, in skin-tight black pants, a sparkly tie and a matching checked jacket and hat, took time out from singing to thank the crowd for its loyalty.

"It's amazing that we're still doing this, and it's amazing that you're still buying our records and coming to our shows," he said. "Thank you, thank you, thank you."

Lead guitarist Keith Richards, whose survival has surprised many who thought he would succumb to drugs and drink, was blunter: "We made it," he said. "I'm happy to see you. I'm happy to see anybody."

But the band's fiery music was no joke, fuelled by strong guest appearances by Taylor, and Mary J. Blige, who shook the house in a duet with Jagger on "Gimme Shelter," and Jeff Beck.

The 50th anniversary show, which will be followed by one more in London, then three in the greater New York area, lacked some of the band's customary bravado ? the "world's greatest rock 'n' roll band" intro was shelved ? and there were some rare nostalgic touches.

The concert began with some early Stones' numbers rarely heard in concert, including the band's cover of the Lennon-McCartney rocker "I Wanna Be Your Man" and a cover of "It's All Over Now," written by Bobby Womack and Shirley Womack.

They didn't shy away from their darker numbers, including "Paint It Black" and "Sympathy for the Devil" ? Jagger started that one wearing a slightly silly black, purple-lined faux fur cape that conjured up his late '60s satanic image.

He even cracked a joke about one of the band's low points, telling the audience it was in for a treat: "We're going to play the entire "Their Satanic Majesty's Request" album now," he said, referring to one of the band's least-loved efforts, a psychedelic travesty that has been largely, mercifully, forgotten.

He didn't make good on his threat.

Jagger seemed more mellow than usual, chatting a bit about the good old days and asking if there was anyone in the crowd who had seen them in 1962, when they first took to the stage.

He said 2012 had been a terrific year for Britain and that the Stones nearly missed the boat, playing no role in the celebration of the Queen's Diamond Jubilee, the London Olympics, or the new James Bond film.

"We just got in under the wire," he said. "We feel pretty good."

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/4e67281c3f754d0696fbfdee0f3f1469/Article_2012-11-26-Britain-Rolling%20Stones/id-d79f9a00ef9b4331bff3ba6a49b90e17

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সোমবার, ২৬ নভেম্বর, ২০১২

US science could face fiscal cliff doom

The American science programs that landed the first man on the moon, found cures for deadly diseases and bred crops that feed the world now face the possibility of becoming relics in the story of human progress.

American scientific research and development stands to lose thousands of jobs and face a starvation diet of reduced funding if politicians fail to compromise and halt the United States' march towards the fiscal cliff's sequestration of federal funds.

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NEWS: What's the Fiscal Cliff?

The Bureau of Labor Statistics reported 1,082,370 U.S. citizens employed in the life sciences, such as biology and genetics, as well as physical and social sciences. Of these, approximately 31,000 stand to lose their jobs if sequestration takes place, according to a study conducted for the Aerospace Industries Association by Steve Fuller, director of the Center for Regional Analysis and professor of public policy at George Mason University.

These potential job losses represent approximately 3 percent of the total life, physical and social science jobs in the United States.

The possible $56.7 billion cut to the the Department of Defense (DOD) budget may result in 14,982 lost science jobs out of a total 325,693 lost, or 4.6 percent of the total DOD jobs cut, according to Fuller's report. Reducing the budgets of other agencies, such as the U.S. Geological Survey, by $59 billion could result in 15,980 science jobs lost, or 3.8 percent of the 420,529 total non-DOD jobs destroyed.

Unfortunately, the loss of research and development jobs is only the tip of the unemployment iceberg the fiscal cliff could create if scientific progress loses funding.

"The 31,000 figure does not include the indirect job losses, such as subcontractors, suppliers and vendors, or the induced job impacts," Fuller told Discovery News. "Induced jobs are those supported by employee's spending on goods and services, so these are unlikely to be STEM (Science, Technology, Engineering and Math) type jobs but rather retail, consumer services, education and health, construction and those types of occupations.

"The direct jobs are clearly the immediate losses and encompass most of the STEM-type jobs," said Fuller. "There will be some subcontractor job losses, including some STEM type jobs. For DOD contracts in general, subcontractor jobs are about 26 percent of the total where the direct jobs are about 30 percent. The remaining job losses, 44 percent, are induced."

NEWS: Fiscal Cliff: Just the Facts

Job losses would be spread across the nation, but certain states would be hit harder than others. The American Association for the Advancement of Science (AAAS) calculated that California would lose the most research and development funding, with a $11.3 million loss. Maryland, Virginia, Massachusetts and Washington D.C. rounded out the list of top five biggest losers.

"We won't really know where the job losses will be until they happen," said Matthew Hourihan, director of the AAAS R&D Budget and Policy Program, "but it will probably be most acute in those states with the most knowledge-intensive workforces, since most of these are substantial performers of federally funded science."

"Not only would research itself suffer, but the cutbacks would likely have ripple effects into the future, as young scientists and science students would have fewer opportunities," said Hourihan. "So the immediate and direct job losses don't really tell the full story, because you'll also have fewer opportunities for new jobs."

The job losses from the fiscal cliff would be tragic enough by themselves, but the loss would also set America further behind other nations in the race towards scientific and technological leadership. The nation which led the race to the moon could find itself looking up to nations it once left Earthbound.

"Sequestration would be dropping an anchor on the science enterprise, while many others are setting their sails," said Hourihan. "As an example, here are some factoids derived from Organization for Economic Cooperation and Development data: since 1999, the US has increased the research intensity of its economy by 10 percent. Over the same period, research intensity in Israel, Finland, and Germany have grown about twice as fast. In Taiwan, it's grown five times as fast. In South Korea, it's grown six times as fast. In China, the number two funder behind us, it's grown ten times as fast."

NEWS: Obama Hints at New Drive on Climate Change

Although he notes it is impossible to put an exact time line on how far back the fiscal cliff's sequestration would set back American science, Hourihan suggests agencies like the National Institute of Health could be set back by a decade or more.

A scarcity of federal research dollars means organizations will have to say no to more promising research. A report by the American Institute of Biological Sciences (AIBS) presented figures stating that the National Science Foundation could lose $586 million, which would result in the grant proposal success rate dropping from 22 percent to 16 percent. The National Institutes of Health would likely fund 700 fewer grants as a result of a $2.5 billion cut, which would represent a drop in the proposal success rate from 19 to 14 percent.

"This means that researchers start spending more time writing grants to keep their labs running and their lab personnel employed," said Robert Gropp, director of public policy at the AIBS. "In essence, they start doing less science ? there time is going to preserving funding. This can certainly slow scientific progress."

Gropp noted that the sequestration cuts would come on top of cuts that some agencies have been taking for a number of years. Funding for the U.S. Geological Survey, for example, has been essentially flat for a number of years. So, another deep cut is going to have a significant impact on the agency.

ANALYSIS: Most Americans Favor Action on Climate Change

New science may be delayed because of the importance of sustaining data monitoring for existing programs, said Gropp. Like the Red Queen in Lewis Carroll's Through the Looking-Glass, it will take all the running scientists can do just to stay in place monitoring the data coming in from existing programs. Cutting funding hamstrings scientists ability to run even faster and move forward.

"I think the federal agencies and the congressional appropriators have worked hard to carefully evaluate scientific research programs," said Gropp. "I think they have made the cuts to programs that were underperforming or of lower priority. I am not sure that there is much more that can be cut without very real and long-term negative ramifications."

? 2012 Discovery Channel

Source: http://www.msnbc.msn.com/id/49958870/ns/technology_and_science-science/

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Watch YouTube And Other Online Streaming Video Files Direct ...

November 25th, 2012 | Tags: Media Player, Multimedia, player, Tools, Utilities, Videolan, videos, VLC, VLC Player | Category: Technology, Website, You Tube

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Man who performed world's first successful kidney transplant dies at 93

BOSTON (AP) ? Dr. Joseph E. Murray, who performed the world's first successful kidney transplant and won a Nobel Prize for his pioneering work, has died at age 93.

Murray's death in Boston at Brigham and Women's Hospital was confirmed Monday by hospital spokesman Tom Langford. No cause of death was immediately announced.

Since the first kidney transplants on identical twins, hundreds of thousands of transplants on a variety of organs have been performed worldwide. Murray shared the Nobel Prize in Physiology or Medicine in 1990 with Dr. E. Donnall Thomas, who won for his work in bone marrow transplants.

"Kidney transplants seem so routine now," Murray told The New York Times after he won the Nobel. "But the first one was like Lindbergh's flight across the ocean."

Murray's breakthroughs did not come without criticism, from ethicists and religious leaders. Some people "felt that we were playing God and that we shouldn't be doing all of these, quote, experiments on human beings," he told The Associated Press in a 2004 interview in which he also spoke out in favor of stem cell research.

In the early 1950s, there had never been a successful human organ transplant. Murray and his associates at Boston's Peter Bent Brigham Hospital, now Brigham and Women's Hospital, developed new surgical techniques, gaining knowledge by successfully transplanting kidneys on dogs. In December 1954, they found the right patients, 23-year-old Richard Herrick, who had end-stage kidney failure, and his identical twin, Ronald Herrick.

Because of their identical genetic background, they did not face the biggest problem with transplant patients, the immune system's rejection of foreign tissue.

After the operation, Richard had a functioning kidney transplanted from Ronald. Richard lived another eight years, marrying a nurse he met at the hospital and having two children.

"Post-operatively the transplanted kidney functioned immediately with a dramatic improvement in the patient's renal and cardiopulmonary status," Murray said in his Nobel lecture. "This spectacular success was a clear demonstration that organ transplantation could be life-saving."

Murray performed more transplants on identical twins over the next few years and tried kidney transplants on other relatives, including fraternal twins, learning more about how to suppress the immune system's rejection of foreign tissue. One patient who received a kidney transplant from a fraternal twin in 1959, plus radiation and a bone marrow transplant to surpress his immune response, lived for 29 more years.

But it was the development of drugs to suppress the body's immune response, a less radical approach than radiation, that made real breakthroughs in transplants possible. In 1962, Murray and his team successfully completed the first organ transplant from an unrelated donor. The 23-year-old patient, Mel Doucette, received a kidney from a man who had died.

Murray continued a long career in plastic surgery, his original specialty, and transplants. He was guided by his own deep religious convictions.

"Work is a prayer," he told the Harvard University Gazette in 2001. "And I start off every morning dedicating it to our Creator."

Murray told the Journal of the American Medical Association in 2004 that he continued to get letters from patients he helped years earlier and from relatives of those who died during the early efforts.

"They often say ... that they are happy to have played some small part in the eventual success of organ transplants," he said, praising the courage of his patients and their families.

Murray was honored at the 2004 Transplant Games, for athletes who have received organ transplants, along with Ronald Herrick, the man who had donated a kidney to his twin brother a half-century earlier.

Murray's interest in transplants developed during his time in the Army during World War II when he was assigned to Valley Forge General Hospital in Pennsylvania while awaiting overseas duty. The hospital performed reconstructive surgery on troops who had been injured in battle.

The burn patients, who were often treated with skin grafts from other people, intrigued Murray.

"The slow rejection of the foreign skin grafts fascinated me," Murray wrote in autobiography for the Nobel Prize ceremony. "How could the host distinguish another person's skin from his own?"

The hospital's chief of plastic surgery, Col. James Barrett Brown, had performed skin grafts on civilians and noticed that the closer the donor and recipient were related, the slower the tissue was rejected. A skin graft between identical twins had taken permanently.

Murray said that was "the impetus" of his study of organ transplantation.

Murray was ever the optimist and kept on his desk a quotation, "Difficulties are opportunities," his son Rick Murray said.

"It reflects the unwavering optimism of a great man who was generous, curious, and always humble," Rick Murray said in a statement released by the hospital.

Source: http://news.yahoo.com/transplant-doc-nobel-winner-murray-dies-boston-021318579.html

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Tips On Landscaping In A Wetter Climate - Las Vegas Landscape

by admin on Saturday, November 24th, 2012 | Comments Off

Everyone dreams of a beautiful yard that is the envy of the neighborhood, yet not that many people understand how to do it. Once you are properly educated, landscaping becomes a lot easier. This article provides good ideas so you can make a beautiful landscape like you dreamed you?d have.

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Create yards that can maintain themselves and prevent weeds from growing. The right design should include weed prevention in the form of attractive, ground-covering plants. Make sure your yard?s plants and flowers are healthy and densely packed. If weeds are not able to get sunlight or the nutrients they need, they won?t be able to grow. For the best results, water consistently and fertilize regularly.

TIP! Time your purchases to save money. Purchase lumber in the wintertime.

Before starting, talk to a professional. Even when creating a landscaping project yourself, it is always best to speak with someone who has this type of experience. Since they have more experience, they can give you advice on what not to do. Professionals can also help even the most experienced landscaper to avoid making mistakes.

There is more to landscaping than just plants. It?s easy to narrow your focus to the plants you?re going to add when planning a landscape. It is important to think about using non-organic elements as well. Large landscaping rocks are a good feature to add. One advantage of non-living landscape features is that they are around year-round, even when the other plants aren?t in bloom.

Prior to making any landscaping changes, have a look at your entire home and yard. Sketch a drawing of your land and house and see what fits in around the property to help you visualize your project better.

TIP! A great way to accent your flower beds is to use ornamental grass. Tall grasses, such as purple fountain grass, can add color, texture and a nice visual break to your flower beds.

Edging can be great for a yard generally, but een as you continue landscaping, use edging to keep everything looking professional. The best place to do some edging is at the point where the grass and mulch meet. This is an important place to focus your maintenance efforts.

Anytime you are considering changing your landscape, you must also thing about the structures that already stand on your property. Consider where sprinklers, cables and air conditioners are placed so landscaping doesn?t affect them. You should always call your utility company before you dig, to avoid a costly or dangerous mistake.

If you want to improve your landscaping, but are low on cash, you might want to look into neighborhood cost sharing. What this entails, is that you and your neighbors can pitch in money and share tools, such as clippers and lawnmowers. Once the community has purchased tools and equipment, you can work out a schedule to determine who gets to use the tools each day.

Native Plants

Try using native plants for landscaping. When planning out your landscape, try to include flowers, trees, and shrubs that are native to your local area. Native plants thrive even in the poorest soils and they could also survive in extreme weather conditions.

Having good relations with your neighbors is important, but one advantage of landscaping is an ability to privatize your property. You can define your space with a fence, or a border created from trees or shrubs. When you combine living landscape elements with non-living, the possibilities are almost endless.

TIP! Plan a yard and garden that will continue to be beautiful throughout the year. This means you should have different plants that will blossom throughout the spring and the summer, and perhaps some pine trees to keep your yard green during the winter months.

Choose native plants for your yard. It is easier to take care of native plants since they can thrive with the normal conditions in your area. This means you won?t have to spend so much time maintaining the plants in your yard. If you want information about local plants, visit any home improvement center or nursery for advice.

Now that you have finished this article, you are no doubt aware that the landscape of your dreams is a real possibility. Keep in mind what you?ve just learned, and put it into practice. The neighbors will be talking about your fantastic new yard in no time.

If you enjoyed reading the article above written by one of our guest blog writers and are considering landscaping services for your home and live in Las Vegas, NV we?ll be happy to be of service to you! You can contact us here.

Tips On Landscaping In A Wetter Climate

Source: http://greengurulandscaping.com/tips-on-landscaping-in-a-wetter-climate-2/

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Puzzle game Quantro now offering online multiplayer

Quantro

Quantro is a puzzle game that we wouldn't blame you if you thought was Tetris at first glance. There are plenty of these types of games out there so what makes this one special? Well now with its latest update, Quantro is offering both local and online multiplayer support -- the latter being in "open beta" now. You can join public lobbies to play against random opponents, or choose to create a private lobby with just friends that you invite.

You can grab a download of Quantro at the Google Play Store link above. If you need a quick primer on the basics of the game, you can take a look at the video below as well.

read more



Source: http://feedproxy.google.com/~r/androidcentral/~3/WwyH98YH9lk/story01.htm

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Energy efficient windows ? Home Improvement: House Plans ...

November 20th, 2012 by admin Leave a reply ?

I must change the windows of my home. My old windows aren't bad looking. But although they go well with the house and I still like them, they are lacking the much needed energy efficiency. Heating and cooling my home takes five times longer than it is supposed to. I talked to the contractor that I always use, and after inspecting them, he told me that is time for windows upgrade. Because I really like the window design I have, I went in search for the similar window style only with a better energy efficiency index. I found something that looks promising at the Nitro Windows store my next door neighbor suggested. I?ll see soon enough how they will do.?

Source: http://redtreeinteractive.com/energy-efficient-windows/

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GLHFCasting ? Real Estate agents

If you have made the choice to buy or sell a home, finding a reputable real estate agent can make this process uncomplicated, less stressful, and more economical. Professional realtors are experienced with predict the housing market and the buying/selling process to help their customers get the best deal at the best time. But there are many agents who may not be right for you and choosing the right one can be difficult. During the selection process, make sure you find out what credentials they have and what tools they can utilize. Pay close attention to the way they talk and listen to you, the upkeep of their office, and how they prefer to be paid. By taking some time, you can find the right realtor that will keep you at the top of the real estate game. Herriman Homes for sale

Source: http://www.glhfcasting.com/real-estate-agents/

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ScienceDaily: Gene News

ScienceDaily: Gene Newshttp://www.sciencedaily.com/news/health_medicine/genes/ Genes and Genetics News. Read today's medical research in genetics including what can damage genes, what can protect them, and more.en-usSat, 24 Nov 2012 07:58:26 ESTSat, 24 Nov 2012 07:58:26 EST60ScienceDaily: Gene Newshttp://www.sciencedaily.com/images/logosmall.gifhttp://www.sciencedaily.com/news/health_medicine/genes/ For more science articles, visit ScienceDaily.New insights into virus proteome: Unknown proteins of the herpesvirus discoveredhttp://www.sciencedaily.com/releases/2012/11/121123092132.htm The genome encodes the complete information needed by an organism, including that required for protein production. Viruses, which are up to a thousand times smaller than human cells, have considerably smaller genomes. Using a type of herpesvirus as a model system scientists have shown that the genome of this virus contains much more information than previously assumed. The researchers identified several hundred novel proteins, many of which were surprisingly small.Fri, 23 Nov 2012 09:21:21 ESThttp://www.sciencedaily.com/releases/2012/11/121123092132.htmScientists describe elusive replication machinery of flu viruseshttp://www.sciencedaily.com/releases/2012/11/121122152928.htm Scientists have made a major advance in understanding how flu viruses replicate within infected cells. The researchers used cutting-edge molecular biology and electron-microscopy techniques to ?see? one of influenza?s essential protein complexes in unprecedented detail. The images generated in the study show flu virus proteins in the act of self-replication, highlighting the virus?s vulnerabilities that are sure to be of interest to drug developers.Thu, 22 Nov 2012 15:29:29 ESThttp://www.sciencedaily.com/releases/2012/11/121122152928.htmProtein folding: Look back on scientific advances made as result of 50-year old puzzlehttp://www.sciencedaily.com/releases/2012/11/121122152910.htm Fifty years after scientists first posed a question about protein folding, the search for answers has led to the creation of a full-fledged field of research that led to major advances in supercomputers, new materials and drug discovery, and shaped our understanding of the basic processes of life, including so-called "protein-folding diseases" such as Alzheimer's, Parkinson's and type II diabetes.Thu, 22 Nov 2012 15:29:29 ESThttp://www.sciencedaily.com/releases/2012/11/121122152910.htmStep forward in regenerating and repairing damaged nerve cellshttp://www.sciencedaily.com/releases/2012/11/121121145638.htm Researchers recently uncovered a nerve cell's internal clock, used during embryonic development. This breakthrough could lead to the development of new tools to repair and regenerate nerve cells following injuries to the central nervous system.Wed, 21 Nov 2012 14:56:56 ESThttp://www.sciencedaily.com/releases/2012/11/121121145638.htmArchitecture of rod sensory cilium disrupted by mutationhttp://www.sciencedaily.com/releases/2012/11/121121145621.htm Using a new technique called cryo-electron tomography, scientists have created a three-dimensional map that gives a better understanding of how the architecture of the rod sensory cilium (part of one type of photoreceptor in the eye) is changed by genetic mutation and how that affects its ability to transport proteins as part of the light-sensing process.Wed, 21 Nov 2012 14:56:56 ESThttp://www.sciencedaily.com/releases/2012/11/121121145621.htmAging: Scientists further unravel telomere biologyhttp://www.sciencedaily.com/releases/2012/11/121121130933.htm Researchers have resolved the structure of that allows a telomere-related protein, Cdc13, to form dimers in yeast. Mutations in this region of Cdc13 put the kibosh on the ability of telomerase and other proteins to maintain telomeres.Wed, 21 Nov 2012 13:09:09 ESThttp://www.sciencedaily.com/releases/2012/11/121121130933.htmDrug resistance biomarker could improve cancer treatmenthttp://www.sciencedaily.com/releases/2012/11/121121130811.htm Cancer therapies often have short-lived benefits due to the emergence of genetic mutations that cause drug resistance. A key gene that determines resistance to a range of cancer drugs has been reported in a new study. The study reveals a biomarker that can predict responses to cancer drugs and offers a strategy to treat drug-resistant tumors based on their genetic signature.Wed, 21 Nov 2012 13:08:08 ESThttp://www.sciencedaily.com/releases/2012/11/121121130811.htmGenome packaging: Key to breast cancer developementhttp://www.sciencedaily.com/releases/2012/11/121121130703.htm Two recent studies delve into the role of chromatin modifying enzymes and transcription factors in tumour cells. In one, it was found that the PARP1 enzyme activated by kinase CDK2 is necessary to induce the genes responsible for the proliferation of breast cancer cells in response to progesterone. In another, extensive work has been undertaken to identify those genes activated by the administration of progesterone in breast cancer, the sequences that can be recognized and how these genes are induced.Wed, 21 Nov 2012 13:07:07 ESThttp://www.sciencedaily.com/releases/2012/11/121121130703.htmShort DNA strands in genome may be key to understanding human cognition and diseaseshttp://www.sciencedaily.com/releases/2012/11/121121130643.htm Previously discarded, human-specific ?junk? DNA represents untapped resource in the study of diseases like Alzheimer?s and autism.Wed, 21 Nov 2012 13:06:06 ESThttp://www.sciencedaily.com/releases/2012/11/121121130643.htmBiomarking time: Methylome modifications offer new measure of our 'biological' agehttp://www.sciencedaily.com/releases/2012/11/121121130633.htm In a new study, researchers describe markers and a model that quantify how aging occurs at the level of genes and molecules, providing not just a more precise way to determine how old someone is, but also perhaps anticipate or treat ailments and diseases that come with the passage of time.Wed, 21 Nov 2012 13:06:06 ESThttp://www.sciencedaily.com/releases/2012/11/121121130633.htmKidney tumors have a mind of their ownhttp://www.sciencedaily.com/releases/2012/11/121121104552.htm New research has found there are several different ways that kidney tumors can achieve the same result -- namely, grow.Wed, 21 Nov 2012 10:45:45 ESThttp://www.sciencedaily.com/releases/2012/11/121121104552.htmMechanism to repair clumped proteins explainedhttp://www.sciencedaily.com/releases/2012/11/121121104416.htm Clumped proteins can be dissolved with the aid of cellular repair systems -- a process of critical importance for cell survival especially under conditions of stress. Researchers have now decrypted the fundamental mechanism for dissolving protein aggregates that involves specific molecular chaperones.Wed, 21 Nov 2012 10:44:44 ESThttp://www.sciencedaily.com/releases/2012/11/121121104416.htmNovel mechanism through which normal stromal cells become cancer-promoting stromal cells identifiedhttp://www.sciencedaily.com/releases/2012/11/121121104401.htm New understanding of molecular changes that convert harmless cells surrounding ovarian cancer cells into cells that promote tumor growth and metastasis provides potential new therapeutic targets for this deadly disease, according to new research.Wed, 21 Nov 2012 10:44:44 ESThttp://www.sciencedaily.com/releases/2012/11/121121104401.htmNew test for tuberculosis could improve treatment, prevent deaths in Southern Africahttp://www.sciencedaily.com/releases/2012/11/121120194932.htm A new rapid test for tuberculosis (TB) could substantially and cost-effectively reduce TB deaths and improve treatment in southern Africa -- a region where both HIV and tuberculosis are common.Tue, 20 Nov 2012 19:49:49 ESThttp://www.sciencedaily.com/releases/2012/11/121120194932.htmEvolution of human intellect: Human-specific regulation of neuronal geneshttp://www.sciencedaily.com/releases/2012/11/121120194926.htm A new study has identified hundreds of small regions of the genome that appear to be uniquely regulated in human neurons. These regulatory differences distinguish us from other primates, including monkeys and apes, and as neurons are at the core of our unique cognitive abilities, these features may ultimately hold the key to our intellectual prowess (and also to our potential vulnerability to a wide range of 'human-specific' diseases from autism to Alzheimer's).Tue, 20 Nov 2012 19:49:49 ESThttp://www.sciencedaily.com/releases/2012/11/121120194926.htmRibosome regulates viral protein synthesis, revealing potential therapeutic targethttp://www.sciencedaily.com/releases/2012/11/121120132906.htm Rather than target RNA viruses directly, aiming at the host cells they invade could hold promise, but any such strategy would have to be harmless to the host. Now, a surprising discovery made in ribosomes may point the way to fighting fatal viral infections such as rabies.Tue, 20 Nov 2012 13:29:29 ESThttp://www.sciencedaily.com/releases/2012/11/121120132906.htmHow does antibiotic resistance spread? Scientists find answers in the nosehttp://www.sciencedaily.com/releases/2012/11/121120121835.htm Microbiologists studying bacterial colonization in mice have discovered how the very rapid and efficient spread of antibiotic resistance works in the respiratory pathogen, Streptococcus pneumoniae (also known as the pneumococcus). The team found that resistance stems from the transfer of DNA between bacterial strains in biofilms in the nasopharynx, the area just behind the nose.Tue, 20 Nov 2012 12:18:18 ESThttp://www.sciencedaily.com/releases/2012/11/121120121835.htmScientists identify inhibitor of myelin formation in central nervous systemhttp://www.sciencedaily.com/releases/2012/11/121120100155.htm Scientists have discovered another molecule that plays an important role in regulating myelin formation in the central nervous system. Myelin promotes the conduction of nerve cell impulses by forming a sheath around their projections, the so-called axons, at specific locations -- acting like the plastic insulation around a power cord.Tue, 20 Nov 2012 10:01:01 ESThttp://www.sciencedaily.com/releases/2012/11/121120100155.htm'Obese but happy gene' challenges the common perception of link between depression and obesityhttp://www.sciencedaily.com/releases/2012/11/121120084725.htm Scientists have uncovered evidence that the gene FTO ? the major genetic contributor to obesity ? is associated with an eight per cent reduction in the risk of depression.Tue, 20 Nov 2012 08:47:47 ESThttp://www.sciencedaily.com/releases/2012/11/121120084725.htmTelomere lengths predict life expectancy in the wild, research showshttp://www.sciencedaily.com/releases/2012/11/121119213144.htm Researchers have found that biological age and life expectancy can be predicted by measuring an individual's DNA. They studied the length of chromosome caps -- known as telomeres -- in a 320-strong wild population of Seychelles Warblers on a small isolated island.Mon, 19 Nov 2012 21:31:31 ESThttp://www.sciencedaily.com/releases/2012/11/121119213144.htmCancer: Some cells don't know when to stophttp://www.sciencedaily.com/releases/2012/11/121119171403.htm Certain mutated cells keep trying to replicate their DNA -- with disastrous results -- even after medications rob them of the raw materials to do so, according to new research.Mon, 19 Nov 2012 17:14:14 ESThttp://www.sciencedaily.com/releases/2012/11/121119171403.htmMultiple sclerosis ?immune exchange? between brain and blood is uncoveredhttp://www.sciencedaily.com/releases/2012/11/121119163301.htm DNA sequences obtained from a handful of patients with multiple sclerosis have revealed the existence of an ?immune exchange? that allows the disease-causing cells to move in and out of the brain.Mon, 19 Nov 2012 16:33:33 ESThttp://www.sciencedaily.com/releases/2012/11/121119163301.htm3-D light switch for the brain: Device may help treat Parkinson's, epilepsy; aid understanding of consciousnesshttp://www.sciencedaily.com/releases/2012/11/121119114249.htm A new tool for neuroscientists delivers a thousand pinpricks of light to individual neurons in the brain. The new 3-D "light switch", created by biologists and engineers, could one day be used as a neural prosthesis that could treat conditions such as Parkinson's and epilepsy by using gene therapy to turn individual brain cells on and off with light.Mon, 19 Nov 2012 11:42:42 ESThttp://www.sciencedaily.com/releases/2012/11/121119114249.htmBlood cancer gene BCL6 identified as a key factor for differentiation of nerve cells of cerebral cortexhttp://www.sciencedaily.com/releases/2012/11/121119093848.htm The cerebral cortex is the most complex structure in our brain and the seat of consciousness, emotion, motor control and language. In order to fulfill these functions, it is composed of a diverse array of nerve cells, called cortical neurons, which are affected by many neurological and neuropsychiatric diseases. Researchers have opened new perspectives on brain development and stem cell neurobiology by discovering a gene called BCL6 as a key factor in the generation of cortical neurons during embryonic brain development.Mon, 19 Nov 2012 09:38:38 ESThttp://www.sciencedaily.com/releases/2012/11/121119093848.htmMinority report: Insight into subtle genomic differences among our own cellshttp://www.sciencedaily.com/releases/2012/11/121118141530.htm Scientists have demonstrated that induced pluripotent stem cells -- the embryonic-stem-cell look-alikes whose discovery a few years ago won this year's Nobel Prize in medicine -- are not as genetically unstable as was thought.Sun, 18 Nov 2012 14:15:15 ESThttp://www.sciencedaily.com/releases/2012/11/121118141530.htmSkin cells reveal DNA's genetic mosaichttp://www.sciencedaily.com/releases/2012/11/121118141524.htm The prevailing wisdom has been that every cell in the body contains identical DNA. However, a new study of stem cells derived from the skin has found that genetic variations are widespread in the body's tissues, a finding with profound implications for genetic screening.Sun, 18 Nov 2012 14:15:15 ESThttp://www.sciencedaily.com/releases/2012/11/121118141524.htmLikely basis of birth defect causing premature skull closure in infants identifiedhttp://www.sciencedaily.com/releases/2012/11/121118141432.htm Geneticists, pediatricians, surgeons and epidemiologists have identified two areas of the human genome associated with the most common form of non-syndromic craniosynostosis premature closure of the bony plates of the skull.Sun, 18 Nov 2012 14:14:14 ESThttp://www.sciencedaily.com/releases/2012/11/121118141432.htmDNA packaging discovery reveals principles by which CRC mutations may cause cancerhttp://www.sciencedaily.com/releases/2012/11/121117184658.htm A new discovery concerning a fundamental understanding about how DNA works will produce a "180-degree change in focus" for researchers who study how gene packaging regulates gene activity, including genes that cause cancer and other diseases.Sat, 17 Nov 2012 18:46:46 ESThttp://www.sciencedaily.com/releases/2012/11/121117184658.htmHepatitis C treatment's side effects can now be studied in the labhttp://www.sciencedaily.com/releases/2012/11/121116161059.htm Adverse side effects of certain hepatitis C medications can now be replicated in the lab, thanks to a research team. The new method aids understanding of recent failures of hepatitis C antiviral drugs in some patients, and could help to identify medications that eliminate adverse effects. The findings may aid the development of safer and more effective treatments for hepatitis C and other pathogens such as SARS and West Nile virus.Fri, 16 Nov 2012 16:10:10 ESThttp://www.sciencedaily.com/releases/2012/11/121116161059.htmReconsidering cancer's bad guyhttp://www.sciencedaily.com/releases/2012/11/121116124644.htm Researchers have found that a protein, known for causing cancer cells to spread around the body, is also one of the molecules that trigger repair processes in the brain.Fri, 16 Nov 2012 12:46:46 ESThttp://www.sciencedaily.com/releases/2012/11/121116124644.htmGene distinguishes early birds from night owls and helps predict time of deathhttp://www.sciencedaily.com/releases/2012/11/121116124551.htm New research shows that a gene is responsible for a person's tendency to be an early riser or night owl -- and helps determine the time of day a person is most likely to die.Fri, 16 Nov 2012 12:45:45 ESThttp://www.sciencedaily.com/releases/2012/11/121116124551.htmClues to cause of kids' brain tumorshttp://www.sciencedaily.com/releases/2012/11/121116091226.htm Insights from a genetic condition that causes brain cancer are helping scientists better understand the most common type of brain tumor in children.Fri, 16 Nov 2012 09:12:12 ESThttp://www.sciencedaily.com/releases/2012/11/121116091226.htmArthritis study reveals why gender bias is all in the geneshttp://www.sciencedaily.com/releases/2012/11/121115210541.htm Researchers have pieced together new genetic clues to the arthritis puzzle in a study that brings potential treatments closer to reality and could also provide insights into why more women than men succumb to the disabling condition.Thu, 15 Nov 2012 21:05:05 ESThttp://www.sciencedaily.com/releases/2012/11/121115210541.htmClass of RNA molecules protects germ cells from damagehttp://www.sciencedaily.com/releases/2012/11/121115172255.htm Passing one's genes on to the next generation is a mark of evolutionary success. So it makes sense that the body would work to ensure that the genes the next generation inherits are exact replicas of the originals. Biologists have now identified one way the body does exactly that.Thu, 15 Nov 2012 17:22:22 ESThttp://www.sciencedaily.com/releases/2012/11/121115172255.htmQuick test speeds search for Alzheimer's drugs: Compound restores motor function and longevity to fruit flieshttp://www.sciencedaily.com/releases/2012/11/121115152655.htm Researchers report that an efficient, high-volume technique for testing potential drug treatments for Alzheimer's disease uncovered an organic compound that restored motor function and longevity to fruit flies with the disease.Thu, 15 Nov 2012 15:26:26 ESThttp://www.sciencedaily.com/releases/2012/11/121115152655.htmProtein-making machinery can switch gears with a small structural change process; Implications for immunity and cancer therapyhttp://www.sciencedaily.com/releases/2012/11/121115133414.htm For the past several years, research has focused on the intricate actions of an ancient family of catalytic enzymes that play a key role in translation, the process of producing proteins. In a new study, scientists have shown that this enzyme can actually also work in another fundamental process in humans.Thu, 15 Nov 2012 13:34:34 ESThttp://www.sciencedaily.com/releases/2012/11/121115133414.htmPlant derivative, tanshinones, protects against sepsis, study suggestshttp://www.sciencedaily.com/releases/2012/11/121115133312.htm Researchers have discovered that tanshinones, which come from the plant Danshen and are highly valued in Chinese traditional medicine, protect against the life-threatening condition sepsis.Thu, 15 Nov 2012 13:33:33 ESThttp://www.sciencedaily.com/releases/2012/11/121115133312.htmStructure of enzyme topoisomerase II alpha unravelled providing basis for more accurate design of chemotherapeutic drugshttp://www.sciencedaily.com/releases/2012/11/121115132903.htm Medical researchers have for the first time described the structure of the active site core of topoisomerase II alpha, an important target for anti-cancer drugs. The type II topoisomerases are important enzymes that are involved in maintaining the structure of DNA and chromosome segregation during both replication and transcription of DNA. One of these enzymes, topoisomerase II alpha, is involved in the replication of DNA and cell proliferation, and is highly expressed in rapidly dividing cancer cells.Thu, 15 Nov 2012 13:29:29 ESThttp://www.sciencedaily.com/releases/2012/11/121115132903.htmNewly discovered enzyme important in the spreading of cancerhttp://www.sciencedaily.com/releases/2012/11/121115132901.htm Enzyme hunters at UiO have discovered the function of an enzyme that is important in the spreading of cancer. Cancer researchers now hope to inhibit the enzyme.Thu, 15 Nov 2012 13:29:29 ESThttp://www.sciencedaily.com/releases/2012/11/121115132901.htmGenetics point to serious pregnancy complication, pre-eclampsiahttp://www.sciencedaily.com/releases/2012/11/121115132613.htm New research has revealed a genetic link in pregnant moms - and their male partners - to pre-eclampsia, a life-threatening complication during pregnancy.Thu, 15 Nov 2012 13:26:26 ESThttp://www.sciencedaily.com/releases/2012/11/121115132613.htmMolecular mechanisms underlying stem cell reprogramming decodedhttp://www.sciencedaily.com/releases/2012/11/121115132344.htm Thanks to some careful detective work, scientist better understand just how iPS cells form ? and why the Yamanaka process is inefficient, an important step to work out for regenerative medicine. The findings uncover cellular impediments to iPS cell development that, if overcome, could dramatically improve the efficiency and speed of iPS cell generation.Thu, 15 Nov 2012 13:23:23 ESThttp://www.sciencedaily.com/releases/2012/11/121115132344.htmSurprising genetic link between kidney defects and neurodevelopmental disorders in kidshttp://www.sciencedaily.com/releases/2012/11/121115132342.htm About 10 percent of kids born with kidney defects have large alterations in their genomes known to be linked with neurodevelopmental delay and mental illness, a new study has shown.Thu, 15 Nov 2012 13:23:23 ESThttp://www.sciencedaily.com/releases/2012/11/121115132342.htmEven moderate drinking in pregnancy can affect a child's IQhttp://www.sciencedaily.com/releases/2012/11/121114172833.htm Relatively small levels of exposure to alcohol while in the womb can influence a child's IQ, according to a new study using data from over 4,000 mothers and their children.Wed, 14 Nov 2012 17:28:28 ESThttp://www.sciencedaily.com/releases/2012/11/121114172833.htmGene nearly triples risk of Alzheimer's, international research team findshttp://www.sciencedaily.com/releases/2012/11/121114171710.htm A gene so powerful it nearly triples the risk of Alzheimer's disease has been discovered by an international team of researchers. It is the most potent genetic risk factor for Alzheimer's identified in the past 20 years.Wed, 14 Nov 2012 17:17:17 ESThttp://www.sciencedaily.com/releases/2012/11/121114171710.htmDiscovery could lead to faster diagnosis for some chronic fatigue syndrome caseshttp://www.sciencedaily.com/releases/2012/11/121114171708.htm For the first time, researchers have landed on a potential diagnostic method to identify at least a subset of patients with chronic fatigue syndrome - testing for antibodies linked to latent Epstein-Barr virus reactivation.Wed, 14 Nov 2012 17:17:17 ESThttp://www.sciencedaily.com/releases/2012/11/121114171708.htmResearch breakthrough could halt melanoma metastasis, study suggestshttp://www.sciencedaily.com/releases/2012/11/121114153227.htm In laboratory experiments, scientists have eliminated metastasis, the spread of cancer from the original tumor to other parts of the body, in melanoma by inhibiting a protein known as melanoma differentiation associated gene-9 (mda-9)/syntenin.Wed, 14 Nov 2012 15:32:32 ESThttp://www.sciencedaily.com/releases/2012/11/121114153227.htmPig genomes provide massive amount of genomic data for human healthhttp://www.sciencedaily.com/releases/2012/11/121114134512.htm Researchers provide a whole-genome sequence and analysis of number of pig breeds, including a miniature pig that serves a model for human medical studies and therapeutic drug testing.Wed, 14 Nov 2012 13:45:45 ESThttp://www.sciencedaily.com/releases/2012/11/121114134512.htmRare parasitic fungi could have anti-flammatory benefitshttp://www.sciencedaily.com/releases/2012/11/121114134054.htm Caterpillar fungi are rare parasites found on hibernating caterpillars in the mountains of Tibet. For centuries they have been highly prized as a traditional Chinese medicine - just a small amount can fetch hundreds of dollars.Wed, 14 Nov 2012 13:40:40 ESThttp://www.sciencedaily.com/releases/2012/11/121114134054.htmCancer therapy: Nanokey opens tumors to attackhttp://www.sciencedaily.com/releases/2012/11/121114113803.htm There are plenty of effective anticancer agents around. The problem is that, very often, they cannot gain access to all the cells in solid tumors. A new gene delivery vehicle may provide a way of making tracks to the heart of the target.Wed, 14 Nov 2012 11:38:38 ESThttp://www.sciencedaily.com/releases/2012/11/121114113803.htmHigh sperm DNA damage a leading cause of 'unexplained infertility', research findshttp://www.sciencedaily.com/releases/2012/11/121114113235.htm New research has uncovered the cause of infertility for 80 per cent of couples previously diagnosed with 'unexplained infertility': high sperm DNA damage.Wed, 14 Nov 2012 11:32:32 ESThttp://www.sciencedaily.com/releases/2012/11/121114113235.htmA risk gene for cannabis psychosishttp://www.sciencedaily.com/releases/2012/11/121114083928.htm The ability of cannabis to produce psychosis has long been an important public health concern. This concern is growing in importance as there is emerging data that cannabis exposure during adolescence may increase the risk of developing schizophrenia, a serious psychotic disorder. Further, with the advent of medical marijuana, a new group of people with uncertain psychosis risk may be exposed to cannabis.Wed, 14 Nov 2012 08:39:39 ESThttp://www.sciencedaily.com/releases/2012/11/121114083928.htmBacterial DNA sequence used to map an infection outbreakhttp://www.sciencedaily.com/releases/2012/11/121113214635.htm For the first time, researchers have used DNA sequencing to help bring an infectious disease outbreak in a hospital to a close. Researchers used advanced DNA sequencing technologies to confirm the presence of an ongoing outbreak of methicillin-resistant Staphylococcus aureus (MRSA) in a Special Care Baby Unit in real time. This assisted in stopping the outbreak earlier, saving possible harm to patients. This approach is much more accurate than current methods used to detect hospital outbreaks.Tue, 13 Nov 2012 21:46:46 ESThttp://www.sciencedaily.com/releases/2012/11/121113214635.htmGenetic variation may modify associations between low vitamin D levels and adverse health outcomeshttp://www.sciencedaily.com/releases/2012/11/121113161506.htm Findings from a study suggest that certain variations in vitamin D metabolism genes may modify the association of low serum 25-hydroxyvitamin D concentrations with health outcomes such as hip fracture, heart attack, cancer, and death.Tue, 13 Nov 2012 16:15:15 ESThttp://www.sciencedaily.com/releases/2012/11/121113161506.htmNew type of bacterial protection found within cells: Novel immune system response to infections discoveredhttp://www.sciencedaily.com/releases/2012/11/121113143656.htm Biologists have discovered that fats within cells store a class of proteins with potent antibacterial activity, revealing a previously unknown type of immune system response that targets and kills bacterial infections.Tue, 13 Nov 2012 14:36:36 ESThttp://www.sciencedaily.com/releases/2012/11/121113143656.htmGlutamate neurotransmission system may be involved with depression riskhttp://www.sciencedaily.com/releases/2012/11/121113134807.htm Researchers using a new approach to identifying genes associated with depression have found that variants in a group of genes involved in transmission of signals by the neurotransmitter glutamate appear to increase the risk of depression.Tue, 13 Nov 2012 13:48:48 ESThttp://www.sciencedaily.com/releases/2012/11/121113134807.htmTargeting downstream proteins in cancer-causing pathway shows promise in cell, animal modelhttp://www.sciencedaily.com/releases/2012/11/121113134230.htm The cancer-causing form of the gene Myc alters the metabolism of mitochondria, the cell?s powerhouse, making it dependent on the amino acid glutamine for survival. Depriving cells of glutamine selectively induces programmed cell death in cells overexpressing mutant Myc. Using Myc-active neuroblastoma cells, a team three priotein executors of the glutamine-starved cell, representing a downstream target at which to aim drugs. Roughly 25 percent of all neuroblastoma cases are associated with Myc-active cells.Tue, 13 Nov 2012 13:42:42 ESThttp://www.sciencedaily.com/releases/2012/11/121113134230.htmEven low-level radioactivity is damaging, scientists concludehttp://www.sciencedaily.com/releases/2012/11/121113134224.htm Even the very lowest levels of radiation are harmful to life, scientists have concluded, reporting the results of a wide-ranging analysis of 46 peer-reviewed studies published over the past 40 years. Variation in low-level, natural background radiation was found to have small, but highly statistically significant, negative effects on DNA as well as several measures of health.Tue, 13 Nov 2012 13:42:42 ESThttp://www.sciencedaily.com/releases/2012/11/121113134224.htmLoss of essential blood cell gene leads to anemiahttp://www.sciencedaily.com/releases/2012/11/121113122220.htm Scientists have discovered a new gene that regulates heme synthesis in red blood cell formation. Heme is the deep-red, iron-containing component of hemoglobin, the protein in red blood cells responsible for transporting oxygen in the blood. The findings promise to advance the biomedical community's understanding and treatment of human anemias and mitochondrial diseases, both known and unknown.Tue, 13 Nov 2012 12:22:22 ESThttp://www.sciencedaily.com/releases/2012/11/121113122220.htmWatching the developing brain, scientists glean clues on neurological disorderhttp://www.sciencedaily.com/releases/2012/11/121113122133.htm Researchers have tracked a gene's crucial role in orchestrating the placement of neurons in the developing brain. Their findings help unravel some of the mysteries of Joubert syndrome and other neurological disorders.Tue, 13 Nov 2012 12:21:21 ESThttp://www.sciencedaily.com/releases/2012/11/121113122133.htmSolving the mystery of aging: Longevity gene makes Hydra immortal and humans grow olderhttp://www.sciencedaily.com/releases/2012/11/121113091953.htm Why do we get older? When do we die and why? Is there a life without aging? For centuries, science has been fascinated by these questions. Now researchers have examined why the polyp Hydra is immortal -- and unexpectedly discovered a link to aging in humans.Tue, 13 Nov 2012 09:19:19 ESThttp://www.sciencedaily.com/releases/2012/11/121113091953.htm

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